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KMID : 0363420200340030018
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Journal of Korean Oriental Pediatrics
2020 Volume.34 No. 3 p.18 ~ p.35
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Review of Clinical Studies of Oral Herbal Medicine Treatment for Pediatric Chickenpox using CNKI Database - Focused on Chinese Randomized Controlled Trials after 2000s -
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Choi Jung-Yoon
Kim Jang-Hyun
Min Sang-Yeon
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Abstract
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Objectives: The purpose of this study is to analyze Chinese randomized controlled trials (RCTs), and to evaluate the effectiveness and safety of the oral herbal medicine treatment for pediatric chickenpox.
Methods: We searched RCTs after 2000s from the China National Knowledge Infrastructure (CNKI). Afterwards, the year of publication, demographic information, duration of chickenpox, intervention, treatment duration, outcome measure, results and adverse events were investigated and analyzed for this study.
Results: 21 RCTs out of 219 studies were collected and analyzed. Although each composition of the herbal medicine was different, they have common ingredients such as ?æðú°Ô¸£¬ß¤Ì¿á¼ðþ, áÂߤù¦æð, ?úìú°Ô¸, ú°øúߤù¦ in order to make efficacy of ?æðú°Ô¸£¬ß¤Ì¿á¼ðþ, áÂߤù¦æð, ?úìú°Ô¸, ú°øúߤù¦. The oral herbal medicine showed better efficacy and safety to improve clinical symptoms such as total efficacy, cure rate, antipyretic time, antipruritic time, scab time, anti-rash time, hospitalization period and herpes recovery time compared to the western medicine treatment.
Conclusions: These results show that the oral herbal medicine treatment on chickenpox in children may be more effective in reducing of clinical symptoms compared to the western medicine treatment.
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KEYWORD
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Pediatric chickenpox, Herbal medicine, TCM, Oral administration, Randomized controlled trial
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